Storyline.
In 2002, an underground Umbrella facility underneath Raccoon City,
"The Hive", experiences a viral outbreak after the T-Virus is intentionally released during a theft. The facility's AI, the "Red Queen", attempts to
stop the outbreak from spreading outside by killing the
research staff. Later that day, an Umbrella special forces unit brakes into the facility's secondary entrance, a mansion in the mountains, to investigate the lack of communication with the
Red Queen. They bring with them three people they find - Alice Abernathy, the lab's security officer; Spence Parks, her husband and co-worker, and Matt Addison, a police officer investigating the area.
Entering the area, they find the facility empty of the research staff and proceed to shut down the AI, loosing four of their team in the process. Little did they know that the AI was stopping the now zombified research staff from escaping. The team is attacked and infected during their escape. Eventually, only three people escape the facility, with one being euthenised along the way. Alice and Matt are taken away by Umbrella for experimentation.
While Alice is unconscious, the new Umbrella team proceeds back down to the lab and forces the
sealed door open; they are quickly killed off by escaped B.O.W.s. Within a matter of hours, the city's roads are walled and its people are being slowly evacuated by Umbrella. After a zombie makes it to
the gate, the gate is closed and the citizens are forced to fend for themselves.
Umbrella sends in the Umbrella Biohazard Countermeasure Force to suppress the outbreak, but they underestimate the combined strength of the zombies and B.O.W.s, and many of them are killed
quickly. Elsewhere, a S.T.A.R.S. team is completely wiped out by Matt Addison, who has been
converted into the "Nemesis" B.O.W. Alice, waking up in an abandoned hospital, finds a group of survivors - Jill Valentine included - and, upon making contact with Dr. Charles Ashford, searches for
his daughter Angela in order for him to give them a way out of the doomed city. Rescuing Angela,
the group heads off to Raccoon City Hall, where the Umbrella paramilitary executive, Timothy Cain, has based himself. Reaching the helicopter on the roof, Charles is executed by Cain. The survivors eventually make it to the helicopter and escape, leaving Cain to be eaten by a resurrected Charles.
The city is destroyed after Umbrella launches a nuclear-tipped missile into city hall.
Alice is injured after the helicopter takes damage, and is left for dead after crashing. An Umbrella
team led by Dr. Sam Isaacs claims her body and experiments on her with the T-Virus. She wakes
up in another facility and escapes using newly-latent psionic powers. Meeting up with the other survivors, they make an attempt to spread word onto the world, who, due to Umbrella's influence,
deny the evidence.
Meanwhile, a Raccoon survivor boards a plane to Los Angeles, and another to Tokyo. Both becomes zombies on arrival and the virus quickly spreads again. By 2007, five years after the Raccoon City incident, human civilisation has collapsed and the mere million-strong survivors are scattered across
the world, always under the constant threat of the infected. Alice uses her psionic powers to defend herself as she makes her way to Las Vegas, where a convoy of survivors also heads off to - due to it being a hotspot for infected crows at one point, the zombies in the area have been wiped out. Alice meets the convoy leader, Claire Redfield, and the two make preparations for camp.
Elsewhere, Dr. Isaacs makes multiple clones of Alice based on DNA collected from her while she was being experimented on five years earlier. He uses their DNA, which was altered by the T-Virus, on a number of zombies in an attempt to cure them of the virus and return them to normality. The
evolved zombies soon escape to Las Vegas, assaulting the convoy en-masse. Alice stumbles onto Isaacs' research facility and battles the monster that he has become. Afterwards, she learns of Albert Wesker, the Umbrella executive working in the shadows, and targets him as her next victim.
Using Isaacs' clones as her army, Alice launches a massive assault on Umbrella's Tokyo
headquarters. However, Wesker, duly informed that Alice is after him, has injected himself with a
new strain of the T-Virus, which gives him enhanced, strength, agility, and regenerative capabilities. Wesker destroys the clones and overpowers the real Alice, injecting her with an anti-virus that
renders her powerless.
Wesker flees to the Arcadia super-tanker, utilizing it as his new base of operations. Alice and Claire track the ship to Los Angeles, where Claire is reuinited with her missing brother, Chris Redfield, who
is leading a handful of survivors. After fighting off the Executioner, Alice and the Redfields confront Wesker on the Arcadia, which contains nearly 2000 plague survivors. They retake the ship, forcing Wesker to flee, but unbeknownst to them, a brainwashed Jill has been ordered to hunt them down.
"The Hive", experiences a viral outbreak after the T-Virus is intentionally released during a theft. The facility's AI, the "Red Queen", attempts to
stop the outbreak from spreading outside by killing the
research staff. Later that day, an Umbrella special forces unit brakes into the facility's secondary entrance, a mansion in the mountains, to investigate the lack of communication with the
Red Queen. They bring with them three people they find - Alice Abernathy, the lab's security officer; Spence Parks, her husband and co-worker, and Matt Addison, a police officer investigating the area.
Entering the area, they find the facility empty of the research staff and proceed to shut down the AI, loosing four of their team in the process. Little did they know that the AI was stopping the now zombified research staff from escaping. The team is attacked and infected during their escape. Eventually, only three people escape the facility, with one being euthenised along the way. Alice and Matt are taken away by Umbrella for experimentation.
While Alice is unconscious, the new Umbrella team proceeds back down to the lab and forces the
sealed door open; they are quickly killed off by escaped B.O.W.s. Within a matter of hours, the city's roads are walled and its people are being slowly evacuated by Umbrella. After a zombie makes it to
the gate, the gate is closed and the citizens are forced to fend for themselves.
Umbrella sends in the Umbrella Biohazard Countermeasure Force to suppress the outbreak, but they underestimate the combined strength of the zombies and B.O.W.s, and many of them are killed
quickly. Elsewhere, a S.T.A.R.S. team is completely wiped out by Matt Addison, who has been
converted into the "Nemesis" B.O.W. Alice, waking up in an abandoned hospital, finds a group of survivors - Jill Valentine included - and, upon making contact with Dr. Charles Ashford, searches for
his daughter Angela in order for him to give them a way out of the doomed city. Rescuing Angela,
the group heads off to Raccoon City Hall, where the Umbrella paramilitary executive, Timothy Cain, has based himself. Reaching the helicopter on the roof, Charles is executed by Cain. The survivors eventually make it to the helicopter and escape, leaving Cain to be eaten by a resurrected Charles.
The city is destroyed after Umbrella launches a nuclear-tipped missile into city hall.
Alice is injured after the helicopter takes damage, and is left for dead after crashing. An Umbrella
team led by Dr. Sam Isaacs claims her body and experiments on her with the T-Virus. She wakes
up in another facility and escapes using newly-latent psionic powers. Meeting up with the other survivors, they make an attempt to spread word onto the world, who, due to Umbrella's influence,
deny the evidence.
Meanwhile, a Raccoon survivor boards a plane to Los Angeles, and another to Tokyo. Both becomes zombies on arrival and the virus quickly spreads again. By 2007, five years after the Raccoon City incident, human civilisation has collapsed and the mere million-strong survivors are scattered across
the world, always under the constant threat of the infected. Alice uses her psionic powers to defend herself as she makes her way to Las Vegas, where a convoy of survivors also heads off to - due to it being a hotspot for infected crows at one point, the zombies in the area have been wiped out. Alice meets the convoy leader, Claire Redfield, and the two make preparations for camp.
Elsewhere, Dr. Isaacs makes multiple clones of Alice based on DNA collected from her while she was being experimented on five years earlier. He uses their DNA, which was altered by the T-Virus, on a number of zombies in an attempt to cure them of the virus and return them to normality. The
evolved zombies soon escape to Las Vegas, assaulting the convoy en-masse. Alice stumbles onto Isaacs' research facility and battles the monster that he has become. Afterwards, she learns of Albert Wesker, the Umbrella executive working in the shadows, and targets him as her next victim.
Using Isaacs' clones as her army, Alice launches a massive assault on Umbrella's Tokyo
headquarters. However, Wesker, duly informed that Alice is after him, has injected himself with a
new strain of the T-Virus, which gives him enhanced, strength, agility, and regenerative capabilities. Wesker destroys the clones and overpowers the real Alice, injecting her with an anti-virus that
renders her powerless.
Wesker flees to the Arcadia super-tanker, utilizing it as his new base of operations. Alice and Claire track the ship to Los Angeles, where Claire is reuinited with her missing brother, Chris Redfield, who
is leading a handful of survivors. After fighting off the Executioner, Alice and the Redfields confront Wesker on the Arcadia, which contains nearly 2000 plague survivors. They retake the ship, forcing Wesker to flee, but unbeknownst to them, a brainwashed Jill has been ordered to hunt them down.